This study aims to identify the reality of Total Quality Management (TQM) implementation and its relationship to certain demographic variables in major public sector hospitals in the southern governorates of Palestine. To achieve this objective, a descriptive-analytical approach was employed. Data was collected using a questionnaire and a comprehensive survey to gather the opinions of the study population, which included 258 male and female employees from senior, middle, and supervisory management positions, as well as medical and support staff in major public sector hospitals. A total of 214 questionnaires were returned. Among the most important findings of the study was the high level of TQM practices in the targeted hospitals, as reflected in its five dimensions: (senior management commitment, patient focus, continuous improvement, teamwork and employee participation, and education and training). The results also showed no statistically significant differences in respondents' opinions regarding TQM and its five dimensions based on gender. However, statistically significant differences were found based on two variables: (medical complex and job classification)................ Keywords: ..............Total Quality Management, upper management support and commitment, beneficiary focus, continuous improvement, participation and work teams, education and training.