This study aimed to know the prevalence of migraines according to ABO blood groups for a sample from the corner area with a size of (260) divided into two groups of males with (130) cases and (130) cases of females. The study reached several results, which were represented by the existence of a relationship between the prevalence of migraines and blood groups, as the most cases of headaches were recorded in the age group between (18 and 28) years and the age group between ( 29 and 39) years, at a rate of 50.76% and 34.23%, respectively, and this is what was agreed. With many studies that have confirmed that the highest rates of migraines occur among age groups between (25 and 50) Years. In addition, blood type A was the effect of the types of migraines, followed by type B, with an incidence of 48.48% and 29.23%, respectively, compared to the rest of the other types. This Agreed with and contradicted some studies. The results of the study confirmed that females are more susceptible to migraines compared to males, and this is what agreed with Some studies have explained this due to the hormonal changes that females are exposed to during the stages of their lives during pregnancy, after childbirth, and during Menstruation. The study recommended paying attention and conducting studies on multiple samples to reach more accurate results, especially molecular studies between blood groups and various diseases to reach conclusive scientific facts to take the necessary preventive measures and procedures to reduce the risks of infection and the spread of diseases among members of society................ Keywords:................Migraine, Blood group, Zawia region, Prevalence rate.