This research contributes to highlighting the value of the aloe vera plant, which belongs to the "liliaceal" family, and has several species widely spread in the world. In our research, we will specifically mention the leaves of the aloe vera plant. This plant has many medical purposes, as it is effective in healing wounds and has an anti-inflammatory effect. Its valuable value depends on the active components that are present in its chemical composition, and among these components, the most important of which are tannins, alkaloids, flavonoids, glycosides, and reducing sugars, which gave positive results for detection. The extract of the leaves of the aloe vera plant also has an inhibitory effect against some types of bacteria, and this was proven in our research by estimating this effectiveness, as we obtained positive results for some strains such as Staphylococcus epidermis, Staphylococcus aureus, Proteus SPP, We also obtained negative results for others, such as Esherichia coli, Klebsiella SPP................... Keywords:........... Aloe Vera, Active Chemical Compounds, Inhibitory Activity Against Some Bacteria, ethyl alcohol 96%, microbial tests